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Non-Coding RNA Webinar |Competitive Endogenous RNA Networks in Cancer

9 July 2025, 16:00 (CEST)

Circular RNAs, MicroRNAs, Positive Feedback Loop, Cancer, Meningioma Recurrence, Competitive Endogenous RNA Network
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Webinar Content

17th Webinar of Non-coding RNA

Competitive Endogenous RNA Networks in Cancer

In this webinar, Prof. Davide Barbagallo (Associate Professor at the Biomedical and Biotechnological Sciences Department, University of Catania, Italy) talks about the potential critical role exerted by circRNA-mediated competitive endogenous RNA (ceRNA) networks in Meningioma recurrence. In particular, Prof. Barbagallo describes the combined in silico and wet approach that led to the identification of a feed-forward gene expression loop mediated by a ceRNA network in recurring Meningiomas, paving the way for the study of this yet relatively unexplored field of research.

In this section, you will find the recordings of this webinar to watch, re-watch and share with your colleagues!

Event Chair

Faculty of Health and Applied Sciences, University of the West of England, Bristol BS16 1QY, UK

Introduction
Bio
Michael was born and raised in Rome as an Italian-Australian. Aged 18 he moved to Australia to read a BSc(Hons) in Genetics at the University of Melbourne. He then moved to Scotland to undertake a PhD at the University of St Andrews. He worked for a year as a postdoctoral Research Associate at St Andrews University, and then for six years at the Medical Research Council Human Genetics Unit in Edinburgh. He moved to the University of the West of England in 2002 where he is now a Professor of Genetics. His main scientific interest is in RNA Biology and its fundamental importance in development and disease.

Keynote Speaker

Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy

Introduction
Bio
Davide Barbagallo is an Associate Professor of Experimental Biology at University of Catania, Italy (https://www.biometec.unict.it/docenti/davide.barbagallo?eng). Davide focused his research on non-coding RNAs since his PhD course, in 2005. In 2010, his PhD thesis was awarded as the best in the field of complex biological systems from the Gioenian Academy. In 2017 he was awarded the Umberto Veronesi Foundation Post-doctoral fellowship and he joined Professor Jørgen Kjems’ non-coding RNA lab, University of Aarhus, Denmark, where he spent 6 months to improve his knowledge on circular RNAs (circRNAs), another class of (mostly) non-coding RNAs, recently discovered as critical regulators of gene expression. During his stay at the non-coding RNA lab, under the tutorship of Dr. Thomas Birkballe Hansen, Davide cloned the sequence of circSMARCA5 into an expression vector and showed the tumor suppressive function and mechanism of action of this circRNA in glioblastoma multiforme. In 2018, Davide got back to University of Catania, at the Department of Biomedical and Biotechnological Sciences where he has continued his work on circRNAs. Davide published more than 60 articles, most of which centered on the study of non-coding RNAs and their involvement in the regulation of gene expression. The main application field of this knowledge is glioblastoma and, more recently, another brain tumor: meningioma. The study that will be described in this talk has been funded by the internal university funding of collaborative research PIACERI 2024-2026 / Linea di Intervento 1 - acronym of the project “MiPiaGli”.

Program

Speaker

Presentation Title

Time in CEST

Time in EDT

Prof. Michael Ladomery

Chair Introduction

4:00–4:05 p.m.

10:00–10:05 a.m.

Dr. Davide Barbagallo

In silico Prediction of a New Competitive Endogenous RNA Network in Recurrent Meningiomas

4:05–4:35 p.m.

10:05–10:35 a.m.

Q&A Session

4:35–4:45 p.m.

10:35–10:45 a.m.

Prof. Michael Ladomery

Closing of Webinar

4:45–4:50 p.m.

10:45–10:50 a.m.

Sponsors and Partners

Organizers

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