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Synthesis of Homochiral R-(+)-2-Methyl-1-butanol
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1  Department of Chemistry, University of Pretoria, Pretoria 0002, South Africa

Abstract: R-(+)-2-Methylbutanol 10a, a building block of several natural products, is commercially unavailable. The total synthesis of 10a in four steps utilising the boronic ester homologation approach is described.
Keywords: boron, stereoselective synthesis, homologation, boronic esters, 2-methylbutanol

 
 
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