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SYNTHESIS AND IN VIVO IMAGISTIC SKIN EVALUATION OF A NEW DISAZO DYE DERIVED FROM 4,4'-DIAMINOSTILBENE-2,2'- DISULFONIC ACID
1 , 2 , 1 , 1
1  University of Medicine and Pharmacy Victor Babeş Timişoara, Faculty of Pharmacy, Piata Eftimie Murgu 2-4, RO-300034 Timişoara, Romania
2  Institute of Chemistry Timisoara of the Romanian Academy, B-dul Mihai Viteazul 24, 300223 Timişoara, Romania

Abstract: The synthesis of a new disazo dyes containing 4,4'-diaminostilbene-2,2'-disulfonic acid as middle component is presented. The synthesized dye was analyzed by thin layer chromatography (TLC), electronic spectra (VIS) and HPLC technique. The structure was elucidated by FT/IR and 13CNMR spectroscopy. The colouristic evaluation of the synthesized dye indicates that this dye could be ranged as a direct dye, suitable for application on cellulosic substrates. Further, an in vivo imagistic skin study was performed in order to evaluate the individual human skin tolerance for this new disazo dye.
Keywords: Azo direct dyes, 4, 4’-diaminostilbene-2,2’-disulfonic acid, Colouristic properties, Imagistic skin evaluation

 
 
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