There have been several advances in understanding the North Atlantic Oscillation (NAO), but there are still uncertainties regarding its level of influence on the tropical climate. Added to this is the fact that most of the studies related to the subject refer to medium and high latitudes, while for the tropical region there is little research that directly addresses the influence of the NAO on the behavior of the oceanographic and atmospheric variables that make up the climate of this region. That is why this work determines the influence of the NAO on the main hydrometeorological events that affect Cuba in the 1999-2016 period. To comply with this, a regression analysis is carried out in the CurveExpert software where the combined influence of the NAO and El Niño-Southern Oscillation (ENSO) on hydrometeorological events is also examined. It was found that the NAO exerts a greater influence on Cuba when it is in its negative phase during the winter season.