Events 7th International Electronic Conference on Medicinal Chemistry

Event submissions

Published

10.3390/ECMC2021-11412

This submission belongs to the session S4. Fighting cancers of the event 7th International Electronic Conference on Medicinal Chemistry

Published date

02 Nov, 2021

Academic Editor

Jean Jacques Vanden Eynde

Citation

Pedro Sobral, Rita Oliveira, Sara Moura, Daniela Alho, Marta Cascante, Silvia Marin, Jorge Salvador, Novel A-ring cleaved glycyrrhetinic acid derivatives: Synthesis and evaluation of antiproliferative activity, in Proceedings of 7th International Electronic Conference on Medicinal Chemistry, 1 November–30 November 2021, MDPI: Basel, Switzerland, doi: 10.3390/ECMC2021-11412

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Novel A-ring cleaved glycyrrhetinic acid derivatives: Synthesis and evaluation of antiproliferative activity

Pedro Sobral ^1,2

Rita Oliveira ^1,2

Sara Moura ^1,2

Daniela Alho ^1,2

Marta Cascante ^3,4

Silvia Marin ^3,4

Jorge Salvador ^1,2

1. Laboratory of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal

2. Center for Neuroscience and Cell Biology, 3000-504 Coimbra, Portugal

3. Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, Diagonal 643, 08028 Barcelona, Spain

4. Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), 28029 Madrid, Spain

Abstract

Keywords

cancer

triterpenoids

glycyrrhetinic acid

antiproliferative activity