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Synthesis of triterpenoid-derived α-acyloxycarboxamides via Passerini reaction
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Academic Editor: György Keglevich
Published:
14 November 2021
by MDPI
in The 25th International Electronic Conference on Synthetic Organic Chemistry
session General Organic Synthesis
Abstract:
Herein we describe the synthesis of a small series of α-acyloxycarboxamides via a facile and efficient one-pot procedure, employing a plant-derived triterpenoid as carboxylic acid component. The products were obtained in overall yields of 25 to 79%, while we scoped the effect of the nature of the aldehyde component on the reaction yields.
Keywords: Passerini reaction (P-3CR); α-acyloxycarboxamides; triterpenoid
