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Alternative and Complementary Approaches to the Asymmetric Synthesis of 3-Aryl or Alkyl Substituted NH Free Isoindolinones
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1  UMR CNRS 8009 "Chimie Organique et Macromoléculaire", Université des Sciences et Technologies de Lille 1, Laboratoire de Chimie Organique Physique, Bâtiment C3(2), F-59655 Villeneuve d'Ascq Cedex, France

Abstract: Alternative and complementary synthetic approaches to the asymmetric synthesis of poly and diversely substituted isoindolinones alkylated or arylated at C-3 have been developed. They mainly differ from the creation of the stereogenic center embedded in the benzolactam nucleus which can be inserted in the models at early or later stage as well in the synthetic process.
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