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A Versatile Method for the Elaboration of Diversely Substituted N-Alkylated and Free-NH Isoindolinones. Application to the Asymmetric Synthesis of the C3-Substituted Models
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1  UMR 8009 "Chimie Organique et Macromoléculaire", associée à l'ENSCL, Laboratoire de Chimie Organique Physique, Bâtiment C3(2), Université des Sciences et Technologies de Lille 1, F-59655 Villeneuve d'Ascq Cédex, France

Abstract: Isoindolinones and their derivatives of generic structure 1, 2 have gained considerable attention due to their diverse physiological and chemotherapeutic activities [1] and for their importance as key intermediates for the construction of various drugs, biologically active compounds [2] and naturally occurring alkaloids [3].
Keywords: n/a