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Substitutions of fluorine atoms and phenoxy groups in the synthesis of quinoxaline 1,4-di-N-oxide derivatives
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1  Unidad en Investigación y Desarrollo de Medicamentos, Centro de Investigación en Farmacobiología Aplicada (CIFA), University of Navarra, 31080 Pamplona, Spain.

Abstract: The unexpected substitution of fluorine atoms and phenoxy groups linked to quinoxaline or benzofuroxan rings is described. The synthesis of 2-benzyl and 2-phenoxy3-methylquinoxaline 1,4-di-N-oxide derivatives was based on the classical Beirut reaction. The experimental conditions (reaction solvent and catalyst) were explored with the aim of obtaining the target compounds.
Keywords: n/a