Previous Article in event
Next Article in event
Next Article in session
Catalytic cycloaddition of diazo compounds based on pharmacologically significant and natural compounds to C60-fullerene
Published:
14 November 2022
by MDPI
in The 26th International Electronic Conference on Synthetic Organic Chemistry
session Bioorganic, Medicinal and Natural Products Chemistry
Abstract:
The data obtained by the authors in the field of carbon cluster chemistry, namely, the catalytic cycloaddition of diazo compounds of modern pharmacologically significant and natural compounds to C60-fullerene under the action of complex Pd-catalysts, are summarized. Cycloaddition reactions of diazoacetates, diazoamides, diazoketones with C60-fullerene, catalyzed by Pd(acac)2-PPh3-Et3Al, with selective formation of methano- and pyrazolinofullerenes, new and promising classes of biologically active derivatives of C60-fullerenes
Keywords: fulleren; diazo compounds; methanofullerenes; homofullerenes; pyrazolinofullerenes, antioxidant activity; cytotoxic activity; metal complex catalysis
