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Highly Efficient Approach to the Synthesis of New Chromeno[2,3-d] Pyrimidine derivatives
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Nourreddine CHOUKCHOU-BRAHAM
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Academic Editor: Julio A. Seijas
Published:
14 November 2022
by MDPI
in The 26th International Electronic Conference on Synthetic Organic Chemistry
session General Organic Synthesis
https://doi.org/10.3390/ecsoc-26-13546
(registering DOI)
Abstract:
5H-chromeno[2,3-d]pyrimidines constitute an important class of heterocyclic compounds having diverse biological activities such as antifungal, anti-tumor, antibacterial, antihypertensive activities. In the continuation of our research aimed at developing new methods for the preparation of new heterocyclic compounds, we present in this work, a simple, efficient, and environmentally approach for the synthesis of new and functionalized chromeno[2,3-d]pyrimidines derivatives by the treatment of 2-amino-3-cyano-4H-chromenes with anhydride acetic under solvent-free conditions
Keywords: 5H-chroméno[2,3-d]pyrimidines, 2-amino-3-cyano-4H-chromene, Solvent-free conditions.
Nourreddine CHOUKCHOU-BRAHAM
