Events The 26th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

10.3390/ecsoc-26-13575 (registering DOI)

This submission belongs to the session S1. General Organic Synthesis of the event The 26th International Electronic Conference on Synthetic Organic Chemistry

Published date

14 Nov, 2022

Academic Editor

Julio A. Seijas

Citation

Alejandro Corona-Díaz, Gustavo Rangel Porras, Rocío Gámez-Montaño, Mahanandaiah Kurva, M.V. Basavanag Unnamatla, Synthesis of carbazolyl imidazo[1,2- α] pyridines via Groebke-Blackburn-Bienayme reaction under green catalyst, in Proceedings of The 26th International Electronic Conference on Synthetic Organic Chemistry, 15 November–30 November 2022, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-26-13575

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Synthesis of carbazolyl imidazo[1,2- α] pyridines via Groebke-Blackburn-Bienayme reaction under green catalyst

Alejandro Corona-Díaz ¹

Mahanandaiah Kurva ¹

M.V. Basavanag Unnamatla ^2,3

Gustavo Rangel Porras ¹

Rocío Gámez-Montaño ¹

1. Departamento de Química, Universidad de Guanajuato, Noria Alta S/N, Col. Noria Alta, Guanajuato 36050, Mexico

2. Centro Conjunto de Investigación en Química Sustentable UAEM-UNAM. Carretera Toluca-Atlacomulco Km 14.5, Universidad Autónoma del Estado de México, Toluca, Estado de México, 50200, México

3. Facultad de Química, Universidad Autónoma del Estado de México. Paseo Colón esq. Paseo Tollocan, 50120, Toluca, Mexico

Abstract

Multicomponent reactions (MCR) are efficient and versatile synthetic tools, they also have several advantages such as high convergence, operational simplicity, atomic economy, friendly conditions, and MCR products are obtained with good to excellent overall yields. The Groebke-Blackburn-Bienaymé (GBB) multicomponent reaction based on isonitriles (MCR-I) in the synthesis of imidazo[1,2-α]pyridines (IMP) under green catalyst like montmorillonite K-10 has been little reported. Therefore, the present work describes the novel ultrasound-assisted one-pot synthesis for analogs of imidazo[1,2-α] pyridines (IMPs) incorporating the carbazole.

Keywords

Green synthesis

Imidazo[1,2-α]pyridines (IMP)

Isocyanide-based multicomponent reactions (I-MCR)

Manuscript

sciforum_066821-done.pdf

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