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Fluorescence Study of the Supramolecular Interactions between Coumarins and Serum Albumin
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1  Dpto. Química Física, Facultade de Ciencias, Universidade de Santiago de Compostela, E-27001 Lugo, Spain

Abstract: In this work we study the supramolecular interactions between fluorescent dyes of the family of aminocoumarins and a protein which is the main responsible for matter transport in blood, the serum albumin. The experimental data obtained by fluorescent titrations are analysed using Principal Components Global Analysis to obtain the equilibrium binding constants and the fluorescence spectra of the dyes bound to the protein. The results obtained for the different aminocoumarins are then compared.
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