Reaction of azaheterylguanidines with trichloroacetonitrile

Anton Dolzhenko; Anna Dolzhenko; Wai-Keung Chui

doi:10.3390/ecsoc-10-01383

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Reaction of azaheterylguanidines with trichloroacetonitrile

Anton V. Dolzhenko

^*,

Anna V. Dolzhenko

Wai-Keung Chui

¹ Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore

Published: 30 November 2006 by MDPI in The 10th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-10-01383

Abstract: Separate reaction of benzimidazolyl-2-guanidine and benzothiazolyl-2-guanidines with trichloroacetonitrile was investigated. 2,4-Diamino[1,3,5]triazino[1,2-a]benzimidazole and 2,4-diimino[1,3,5]triazino[2,1-a][1,3]benzothiazoles were found to be products of the reaction. The structures of the compounds obtained were established using ¹H NMR spectroscopy.

Keywords: triazines, benzimidazoles, benzothiazoles, guanidines, cyclization

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