Marijuana has been used for decades, and in recent years, interest in its medical qualities has grown. Cannabinoid medications such as dronabinol, nabilone, and nabiximols have been developed as a result of research into their therapeutic characteristics. Marijuana use disorder is becoming more common among marijuana users. Marijuana is an illegal narcotic that is becoming increasingly popular among teenagers and young people, and it is harmful to human health. This review examines the most common concerns that individuals have concerning marijuana use and its impact on human health. The review focuses on the consequences and severity of the effects on human living, including physical, mental, emotional, and behavioral changes. According to this study, the most often used illicit substance (marijuana) has an active ingredient called delta-9-tetrahydrocannabinol (THC), which causes mind-altering effects. THC, the main element in marijuana, goes throughout the body, including the brain, to generate its numerous effects when smoked. THC binds to receptors known as cannabinoid receptors. THC binds to cannabinoid receptors on nerve cells in the brain, altering their function. "Are there treatments for marijuana abusers?" and "Can marijuana be used as a type of medication in humans?" are two of the concerns discussed.