This scientific paper delves into the effects of water stress on grapevines, specifically focusing on gene expression and polyphenol production. We conducted a controlled greenhouse experiment with three hydric conditions and analyzed the expression of genes related to polyphenol biosynthesis. Our results revealed significant differences in the expression of ABCC1, a gene linked to anthocyanin metabolism, under different irrigation treatments. These findings highlight the importance of anthocyanins in grapevine responses to abiotic stresses. By integrating genomics, metabolomics, and systems biology, this study contributes to our understanding of grapevine physiology under water stress conditions and offers insights for developing sensor technologies for real-world applications in viticulture.