Abstract

The antibacterial and anticancer capabilities of some metallic nanoparticles made from plants are the main focus of this work. Three distinct nanoparticles were tested for their antibacterial and anticancer properties against four cancerous cell lines (Prostate cancer, lungs A549, HeLa and MCF-7) and five pathogenic microbes (Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa and Escherichia coli) bacteria, as well as one yeast (Candida albicans). Metallic nanoparticles from the plants Ajuga macrosperma (FeONPs), Leucas cephalotes (AgNPs), and Abies pindrow royle (CuONPs) were tested for their antibacterial capabilities using the agar-well diffusion method and their ability to fight cancer using the MTS and MTT assays. According to the findings, the majority of the metallic nanoparticles possessed antibacterial qualities having zones of inhibition (ZOI) of 21 mm and 19 mm, respectively, the CuONPs and AgNPs of A. pindow royle and L. cephalotes showed the strongest potential against Pseudomons aeruginosa. The zone of inhibition (ZOI) of A. pindrow royle's CuoNPs and L. cephalotes’s AgNPs was 15 mm 16 mm , 18 mm zone of inhibition respectively, indicating the highest potential against Escherichia coli., Candida albicans and Staphylococcus aureus. It was discovered also that the CuONPs and FeONPs of A. pindrow royle and A. macrosperma were found to have the most potential against the MCF-7 cancer cell line. Prostate cancer and lung cancer (A549) cell lines were the ones that responded most favorably to the AgNPs of L. cephalotes.