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2,3-dihydrobenzo[b][1,4]dioxine N-alkylation using various proton catalysts
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Academic Editor: Humbert G. Díaz
Published:
23 December 2023
by MDPI
in MOL2NET'23, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 9th ed.
congress CHEMBIO.MOL-09: Org. Chem., Med. Chem., Mol. Biol., & Pharm. Industry Congress, Paris, France-Fargo, USA, 2023.
Abstract:
The majority of the compounds that are created using 2,3-dihydrobenzo[b][1,4]dioxine have pharmacological qualities and are employed as synthesis intermediates to create a variety of medications and medicinal substances that are used to treat different illnesses that affect the human body. Thus, the N-alkylation reaction between 2-(2-hydroxyethyl)isoindoline-1,3-dione and 2,3-dihydrobenzo[b][1,4]dioxine was examined in this study. It was investigated how different proton catalysts affected the N-alkylation process. The resulting compound's structure was examined by the application of physico-chemical study methods.
Keywords: proton catalyst, N-alkylation, spectrum analysis, 2-(2-hydroxyethyl)isoindoline-1,3-dione, 2,3-dihydrobenzo[b][1,4]dioxine
Comments on this paper
Maider Baltasar Marchueta
3 January 2024
Dear authors thank you for your support to the conference.
Now we closed the publication phase and launched the post-publication phase of the conference. REVIEWWWERS Brainstorming Workshop is now open until January 25th. MOL2NET committee, authors, and social media followers worldwide are invited to post questions/answers and comments about papers. Please kindly post your public Answers (A) to the following questions in order to promote interchange of scientific ideas.
My Questions (Q) to you:
Q1. How does the choice of proton catalysts impact the N-alkylation reaction between 2-(2-hydroxyethyl)isoindoline-1,3-dione and 2,3-dihydrobenzo[b][1,4]dioxine
Q2. and what are the implications for the synthesis of pharmacologically relevant compounds?
Dear author thanks in advance for your kind support answering the questions.
Now, the conference publication phase is close but you can answer here directly as a post-publication comment.
Last but not least, please become a verified REVIEWWWER of our conference by making questions to other papers in different Mol2Net congresses. Commenting steps: login, go to papers list, select paper, write comment, click post comment.
Happy new year 2024.
Thanks and kind regards,
CHEMBIOMOL Committee Assistant, Maider Baltasar Marchueta.
Now we closed the publication phase and launched the post-publication phase of the conference. REVIEWWWERS Brainstorming Workshop is now open until January 25th. MOL2NET committee, authors, and social media followers worldwide are invited to post questions/answers and comments about papers. Please kindly post your public Answers (A) to the following questions in order to promote interchange of scientific ideas.
My Questions (Q) to you:
Q1. How does the choice of proton catalysts impact the N-alkylation reaction between 2-(2-hydroxyethyl)isoindoline-1,3-dione and 2,3-dihydrobenzo[b][1,4]dioxine
Q2. and what are the implications for the synthesis of pharmacologically relevant compounds?
Dear author thanks in advance for your kind support answering the questions.
Now, the conference publication phase is close but you can answer here directly as a post-publication comment.
Last but not least, please become a verified REVIEWWWER of our conference by making questions to other papers in different Mol2Net congresses. Commenting steps: login, go to papers list, select paper, write comment, click post comment.
Happy new year 2024.
Thanks and kind regards,
CHEMBIOMOL Committee Assistant, Maider Baltasar Marchueta.
