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Development of UV Spectrophotometric Methods and Validation for Estimation of Dapagliflozin in Bulk and Tablet Dosage Form by Absorbance Maxima and Area Under the Curve Method
Published:
24 December 2023
by MDPI
in MOL2NET'23, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 9th ed.
congress CHEMBIO.MOL-09: Org. Chem., Med. Chem., Mol. Biol., & Pharm. Industry Congress, Paris, France-Fargo, USA, 2023.
Abstract:
UV spectrophotometric method was developed for the determination of dapagliflozin in pure form and in tablets. The method was developed using methanol and water as diluents. The results were achieved by using two methods: absorbance maxima and area under the curve method. All the parameters were chosen according to ICH [Q2(R1)] guideline and validated statistically using RSD and %RSD. The results of validation parameters were within the range. The developed method is accurate and precise.
Keywords: Dapagliflozin; antidiabetic agent; UV spectrophotometry, validation parameters
Comments on this paper
Maider Baltasar Marchueta
4 January 2024
Dear authors thank you for your support to the conference.
Now we closed the publication phase and launched the post-publication phase of the conference. REVIEWWWERS Brainstorming Workshop is now open until January 25th. MOL2NET committee, authors, and social media followers worldwide are invited to post questions/answers and comments about papers. Please kindly post your public Answers (A) to the following questions in order to promote interchange of scientific ideas.
My Questions (Q) to you:
Q1. How does the choice of diluents, specifically methanol and water, affect the accuracy and precision of the UV spectrophotometric method for determining dapagliflozin in pure form and tablets?
Dear author thanks in advance for your kind support answering the questions.
Now, the conference publication phase is close but you can answer here directly as a post-publication comment.
Last but not least, please become a verified REVIEWWWER of our conference by making questions to other papers in different Mol2Net congresses. Commenting steps: login, go to papers list, select paper, write comment, click post comment.
Happy new year 2024.
Thanks and kind regards,
CHEMBIOMOL Committee Assistant, Maider Baltasar Marchueta.
Now we closed the publication phase and launched the post-publication phase of the conference. REVIEWWWERS Brainstorming Workshop is now open until January 25th. MOL2NET committee, authors, and social media followers worldwide are invited to post questions/answers and comments about papers. Please kindly post your public Answers (A) to the following questions in order to promote interchange of scientific ideas.
My Questions (Q) to you:
Q1. How does the choice of diluents, specifically methanol and water, affect the accuracy and precision of the UV spectrophotometric method for determining dapagliflozin in pure form and tablets?
Dear author thanks in advance for your kind support answering the questions.
Now, the conference publication phase is close but you can answer here directly as a post-publication comment.
Last but not least, please become a verified REVIEWWWER of our conference by making questions to other papers in different Mol2Net congresses. Commenting steps: login, go to papers list, select paper, write comment, click post comment.
Happy new year 2024.
Thanks and kind regards,
CHEMBIOMOL Committee Assistant, Maider Baltasar Marchueta.
