Use of a new hydrophilic phosphonic phosphines (DPPA). Heck Reaction in Aqueous Medium under Microwave Irradiation.

Didier Villemin; Belkacem Nechab; F. Sardina

doi:10.3390/ecsoc-2-01674

Previous Article in event

Enantiospecific, Stereoselective Synthesis of Enantiomerically Pure Aziridine-2-carboxylic Acids from Aspartic Acid

Next Article in event

Synthesis and investigation of 2- hydroxyaryl(5-methylfur-2-yl) alkanes.

Use of a new hydrophilic phosphonic phosphines (DPPA). Heck Reaction in Aqueous Medium under Microwave Irradiation.

Didier Villemin

^*,

Belkacem Nechab

F. Javier Sardina

¹ Ecole Nationale Superieure d' Ingenieurs de Caen, I.S.M.R.A., Universite de Caen UMR CNRS 6507, 6 Boulevard du Marechal Juin F-14050 Caen Cedex, France

Published: 01 November 1998 by MDPI in The 2nd International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-2-01674

Abstract: The Heck reaction is efficiently and rapidly obtained by a palladium-catalysed reaction in water performed in a Teflon autoclave under microwave irradiation with a commercial microwave oven. Water soluble phosphine-ligand catalysts and phase transfer catalysis conditions are used.

Keywords: Heck reaction, Microwaves, Phase-transfer catalysis, Water-soluble phosphine, LogP, DPPA

View paper

56 Reads
0 Recommendations

Didier Villemin

Belkacem Nechab

F. Sardina