A Simple Synthesis of the Aryloxy- or Arylthio- derivatives of 2-Benzothiazolyl Stilbenes

Margita Lacova; Dusan Loos; Jarmila Chovancova; Stefan Spisiak; Anna Fabiane

doi:10.3390/ecsoc-2-01683

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A Simple Synthesis of the Aryloxy- or Arylthio- derivatives of 2-Benzothiazolyl Stilbenes

Margita Lacova

^{*

1},

Dusan Loos

²,

Jarmila Chovancova

¹,

Stefan Spisiak

³,

Anna Fabiane

¹ Department of Organic chemistry, Faculty of Science, Comenius University, SK-842 15 Bratislava, Slovakia
² Institute of Chemistry, Faculty of Science Comenius University, SK- 84215 Bratislava, Slovakia
³ Biotika, a.s., Slovenska Lupca, Slovakia

Published: 01 November 1998 by MDPI in The 2nd International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-2-01683

Abstract: Synthesis of 2-(b -(aryl-X)styryl)benzothiazoles (2a - 2z) (X = 0, O, S) from aromatic or heterocyclic aldehydes and 2-naphthylmethyl-, 2-aryloxymethyl- or 2-arylthiomethyl benzothiazoles is reported. Phthalides 4a - 4f were prepared by Gabriel modification of Perkin synthesis. Products were confirmed by NMR spectral and elemental analysis. Prepared compounds were tested on herbicidal and growth - regulating activity. The semiempirical AM1 quantum - chemical method has been used to study an optimal conformation and heats of formation.

Keywords: Aryloxymethylbenzothiazoles, Arylthiomethylbenzothiazoles, Aldol Condensation, Phthalides, AM1 Semiempirical calculations.

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Margita Lacova

Dusan Loos

Jarmila Chovancova

Stefan Spisiak

Anna Fabiane