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Phthalides and Chromones from 4-Coumarinacetic acids, Study of Beneficial Effects of Microwave Irradiation on Synthesis.
* 1 , 2 , 1 , 2
1  Department of Organic Chemistry, Comenius University, Mlynska dolina CH-2, SK- 842 15 Bratislava, Slovakia
2  Institute of Chemistry, Faculty of Natural Sciences, Comenius University, Mlynska dolina CH-2, SK-842 15 Bratislava

Abstract: 3-(4-Coumarinylmethylene)phthalides and 2-, or 3-(4-coumarinylethenyl)-4-chromones were prepared by condensation reaction. Beneficial effect of microwave irradiation on length of reaction time was investigated. Some subsequent reactions of these derivatives with nucleophiles are described. Nucleophile attack is studied by AM1 theoretical method.
Keywords: 3-formylchromones, dicarboxylic acid anhydrides, condensation reaction, pyridine derivatives