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Synthesis of Homochiral R-(+)-2-Methyl-1-butanol
Published:
11 September 2000
by MDPI
in The 4th International Electronic Conference on Synthetic Organic Chemistry
session General Organic Synthesis
Abstract: R-(+)-2-Methylbutanol 10a, a building block of several natural products, is commercially unavailable. The
total synthesis of 10a in four steps utilising the boronic ester homologation approach is described.
Keywords: boron, stereoselective synthesis, homologation, boronic esters, 2-methylbutanol