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Synthesis of the pyrido[2,3,4-kl]acridine ring system common to several cytotoxic marine alkaloids
Published: 11 September 2000 by MDPI in The 4th International Electronic Conference on Synthetic Organic Chemistry session Bioorganic Chemistry and Natural Products
Abstract: An efficient five-step synthesis of the pyrido[2,3,4-kl]acridin-8-one system is described, using a Suzuki coupling of a 4-iodoquinoline and a oxidative demethylation with cobalt trifluoride as the key steps.