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Synthesis of the pyrido[2,3,4-kl]acridine ring system common to several cytotoxic marine alkaloids
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1  Departamento de Química Orgánica y Farmacéutica, Facultad de Farmacia. Universidad Complutense, 28040 Madrid, Spain.

Abstract: An efficient five-step synthesis of the pyrido[2,3,4-kl]acridin-8-one system is described, using a Suzuki coupling of a 4-iodoquinoline and a oxidative demethylation with cobalt trifluoride as the key steps.
Keywords: n/a