Unexpected Result of Alkaline Hydrolysis of Biginelli Compounds

Anatoly Shutalev

doi:10.3390/ecsoc-8-01941

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A New Approach to the Synthesis of Biginelli Compounds and Their Analogues

Unexpected Result of Alkaline Hydrolysis of Biginelli Compounds

Anatoly D. Shutalev

¹ Department of Organic Chemistry, M.V. Lomonosov State Academy of Fine Chemical Technology, 119571 Moscow, Russian Federation

Published: 01 November 2004 by MDPI in The 8th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-8-01941

Abstract: 4-Aryl-6-styryl-1,2,3,4-tetrahydropyrimidin-2-ones are final products of transformation of ethyl 4-aryl-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylates in alkaline hydrolytic conditions.

Keywords: ethyl 4-aryl-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylates; Biginelli compounds; 4-aryl-6-styryl-1,2,3,4-tetrahydropyrimidin-2-ones; alkaline hydrolysis; decarboxylation; coupling

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Anatoly Shutalev