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Synthesis of Arylamino-thieno-oxobutanamides and Reactivity Studies on the Cyclisation with the Lawesson's Reagent
* 1 , 1 , 2
1  Departamento de Química, Universidade do Minho, Campus de Gualtar, 4710-057 Braga, Portugal
2  Laboratoire d´Ingénierie Moléculaire et Biochimie Pharmacologique, Université de Metz 1, Boulevard Arago, Metz Technopôle, 57078 Metz Cedex 3, France

Abstract: 1-aryl-2-thienyl-substituted pyrroles and 5-arylamino-2,2´-bithiophenes were synthesized by treatment of arylamino-thieno-oxobutanamides with Lawesson´s reagent. These in turn were prepared by direct amidation of 4-oxo-(2-thienyl)butanoic acid through DCC/BtOH mediated reactions.
Keywords: arylamino-thieno-oxobutanamides, Lawesson´s reagent, 1-aryl-2-(2´-thienyl)pyrroles, 5-arylamino-2,2´-bithiophenes, non-linear optical material, NLO applications.