Solvent-Free, Efficient Synthesis of 2,5-piperazinediones from BOC-Protected Dipeptides under Microwave Irradiation

Alberto López-Cobeñas; Pilar Cledera; J. Domingo Sánchez; Rafael Pérez-Contreras; Pilar López-Alvarado; M. Ramos; Carmen Avendaño; J. Menéndez

doi:10.3390/ecsoc-8-01985

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Solvent-Free, Efficient Synthesis of 2,5-piperazinediones from BOC-Protected Dipeptides under Microwave Irradiation

Alberto López-Cobeñas

Pilar Cledera

J. Domingo Sánchez

Rafael Pérez-Contreras

Pilar López-Alvarado

M. Teresa Ramos

Carmen Avendaño

J. Carlos Menéndez

¹ Departamento de Química Orgánica y Farmacéutica, Facultad de Farmacia, Universidad Complutense, 28040 Madrid, Spain

Published: 01 November 2004 by MDPI in The 8th International Electronic Conference on Synthetic Organic Chemistry session Symposium on Microwave Assisted Synthesis

https://doi.org/10.3390/ecsoc-8-01985

Abstract: Microwave irradiation of a variety of BOC-protected dipeptide esters provides the corresponding 2,5-piperazinediones in short reaction times and good to excellent yields.

Keywords: n/a

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