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Resin-bound Isothiocyanates and their Synthetic Equivalents as Intermediates for the Solid-Phase Synthesis of Substituted Thiophenes
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1  Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Maaloev, Denmark

Abstract: Highly reactive, polystyrene-bound thiocarbamoyl chlorides and isothiocyanates have been used as key intermediates in a new, robust solid-phase synthesis of substituted thiophenes.
Keywords: solid-phase synthesis, thiophenes, combinatorial chemistry.