The behavioral response of Hyperaspis maindroni to different cassava (Manihot esculenta) varieties was assessed using multi-choice pot culture and olfactometer bioassays. Four cassava varieties, viz. Sree Athulya (resistant), CO3 (moderately resistant), Kunguma Rose (susceptible), and Mulluvadi (highly susceptible), were tested under both healthy and cassava mealybug (CMB)-infested conditions. In the multi-choice pot culture bioassay, H. maindroni exhibited significant variations in its attraction among the cassava varieties. The highest attraction was observed in CMB-infested MVD-1 (11.80 nos.), followed by Kunguma Rose (8.40 nos.), CO3 (5.80 nos.), and Sree Athulya (3.60 nos.). The dual-choice bioassays confirmed that MVD-1 was the most preferred variety, showing the highest attraction percentages when paired with the other varieties (86.60% vs. Sree Athulya, 76.60% vs. CO3, and 65.90% vs. Kunguma Rose). In the olfactometer bioassay, H. maindroni was most attracted to the arm containing the CMB alone (9.10 nos.), followed by healthy MVD-1 (3.40 nos.), Kunguma Rose (2.80 nos.), CO3 (2.40 nos.), and Sree Athulya (1.20 nos.). When testing the CMB-infested leaves, MVD-1 attracted the highest number of H. maindroni (6.90 nos.), followed by Kunguma Rose (5.10 nos.), CO3 (4.30 nos.), and Sree Athulya (3.20 nos.), while the arm with CMB alone had the lowest attraction (0.30 nos.). These findings highlight the strong preference of H. maindroni for CMB-infested MVD-1, emphasizing the role of plant resistance levels in host selection. Understanding these interactions can aid in developing effective pest management strategies for cassava crops.