Introduction: Rhyzopertha dominica, Sitophilus oryzae, Trogoderma granarium, and Tribolium castaneum are serious stored-product pests. The pyrethroids inhibit neurotransmission by affecting the function of sodium channels in the nervous system. The anthranilic diamides disturb calcium homeostasis and cause arthropod mortality by specifically activating arthropod ryanodine receptors. The use of combinations of insecticides with different modes of action is more effective compared to single applications.

Methods: A formulation containing the active ingredients λ-cyhalothrin (pyrethroid) plus chlorantraniliprole (anthranilic diamide) was tested in various doses (0.01–5 ppm) against S. oryzae, T. granarium, T. castaneum, and R. dominica on wheat, rice, and maize in laboratory mortality and persistence mortality/progeny production bioassays.

Results: In all bioassays (laboratory and persistence), S. oryzae and R. dominica proved to be the most susceptible species, followed by T. castaneum and T. granarium. The same pattern was noted for progeny production in laboratory and persistence bioassays. Among the tested commodities, wheat led to higher mortality rates compared to rice and maize.

Conclusions: The efficiency of λ-cyhalothrin plus chlorantraniliprole was affected by various biotic and abiotic parameters, such as insect species, commodities, exposure intervals, and doses. The need for innovative and efficient techniques to improve protection in storage facilities is growing because of the limited number of approved grain protectants used in stored products. This research has shed light on the possible application of λ-cyhalothrin plus chlorantraniliprole in storage conditions by combining various parameters.