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Navigating the Challenges of Antibiotic Stewardship
1  Amity University Haryana, Haryana 122412, India
Academic Editor: Marc Maresca

Abstract:
  1. Introduction
  • Background:
    • Antimicrobial resistance (AMR) poses a significant global health threat, increasing morbidity, mortality, and healthcare costs.
    • The WHO has recognized the urgency of this issue and emphasized the need for multi-sectoral collaboration to combat AMR.
  • Significance:
    • Antibiotic Stewardship Programs (ASPs) are crucial for mitigating AMR by optimizing antibiotic use, reducing unnecessary prescriptions, controlling infection spread, and improving patient outcomes.
    • Effective ASPs can contribute to preserving the effectiveness of existing antibiotics for future generations.
  • Research Question:
    • What are the primary obstacles encountered in the successful implementation and long-term sustainability of ASPs within healthcare settings?
    • 2. Methods
  • Literature Review:
    • A comprehensive literature review was conducted using major databases (PubMed, Scopus, Web of Science, Embase, and the Cochrane Library).
    • Relevant articles were identified using a combination of relevant keywords.
    • Data were systematically extracted from selected articles, including information on the types of challenges encountered, strategies to overcome these challenges, and the outcomes of implementation strategies.
  • Data Analysis:
    • Qualitative analysis was conducted to identify and categorize common themes and patterns in the challenges encountered during ASP implementation.
    • If applicable, quantitative analysis was performed to further analyze and interpret the extracted data.
    • 3. Results
  • Key Challenges identified were as follows:
    • Resource Limitations;
    • Organizational Barriers;
    • Patient-Related Factors;
    • External Pressures.

Keywords: Antibiotic, Stewardship, Antimicrobial, Resistance, AMR, ASP
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