The petrochemical industry emits large amounts of nitrogen oxides (NOx). It is the second source of volatile organic compounds (VOCs), which, through photochemical reactions, can form tropospheric ozone (O₃) and, together with geographic and meteorological conditions, determine pollution's spatial and temporal behavior. The objective of this study is to assess the influence of air pollutants NOx, NO₂, and NO, as well as meteorological factors, on O₃ concentration levels in the city of Cadereyta, Nuevo Leon, which is characterized by its petrochemical industry as part of the metropolitan area of ​​Monterrey, Mexico. The data were analyzed using the Spearman correlation coefficient, identifying a weak to moderate negative association between NOx and NO₂ with O₃ in the spring season and a null relationship in the summer. However, the fall and winter seasons observed a moderate to strong negative relationship. Subsequently, a multiple linear regression analysis determined the influence of air pollutants NOx, NO₂, and NO, as well as meteorological factors, on O₃ concentration levels. In this sense, when the concentration levels of NOx and NO₂ decrease, the concentration of O₃ will increase proportionally according to the year's season. The prediction model obtains a coefficient of determination (R²) of 0.61 and a value in the root-mean-square error (RMSE) metric of 0.0107 ppm. In the prediction model, all variables presented a significant effect on the interpretation of the dependent variable, and the independent variables that provided the most significance in the variation in the concentration levels of O₃ were NOx and NO₂.