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Optimization Process for Increasing the Yield of Crude Alkaloid from Litsea polyantha Juss. bark
Published:
03 November 2014
by MDPI
in The 18th International Electronic Conference on Synthetic Organic Chemistry
session Bioorganic, Medicinal and Natural Products Chemistry
Abstract: Litsea polyantha Juss. (Lauraceae) also known as Litsea monopetala Roxb. is a small to medium sized evergreen tree distributed chiefly in tropical and subtropical Asia, Australia and the Pacific Islands. The bark of Litsea polyantha Juss. has a long history of medicinal use among the traditional healers of Oraon and Munda community of Jharkhand (India). In this work, optimization process for increasing the yield of crude alkaloid from Litsea polyantha Juss. bark was performed by taking pH and temperature as the factors influencing the yield. With the help of yield optimization by 22 factorial design the percentage yield of crude alkaloid was increased from 3.8% w/w to 17.3% w/w.
Keywords: Factorial design; Litsea polyantha; alkaloids; plant extracts; ethnopharmacology