Natural products have consistently attracted scientific interest as promising sources for the development of new and effective therapies due to their potential benefits and relatively low risk of adverse effects. Royal Jelly is a natural product with exceptional biological characteristics, a broad apitherapeutic spectrum and great demand in the pharmaceutical and food industries due to its nutritional properties. It has been shown to inhibit a wide range of bacterial strains, making it a promising candidate for combating microbial infections. Aloe vera is known for its benefits for the skin, acting as a moisturizer and healer for conditions like burns and acne; meanwhile, Royal Jelly offers anti-inflammatory, antioxidant and anti-aging effects due to its rich nutrient profile, although studies are ongoing to fully establish its therapeutic potential. The combined use of Aloe vera and Royal Jelly holds potential for enhancing the body’s defense mechanisms against cellular stress, although more research is needed.
The current research objective is related to the synthesis, analysis and characterization of the physicochemical and pharmaceutical properties of the mixture of Royal Jelly and Aloe vera to form a biocomposite hydrogel of natural origin for use in therapeutic and anti-aging applications. The prepared hydrogel was comprehensively analyzed and exhibited organoleptic features and favorable properties for wound dressing applications in terms of its morpho-structural characteristics, swelling, pH and spreadability. The materials were analyzed by Fourier transform infrared (FT-IR) and Raman spectroscopy, while morphological analysis was performed by scanning electron microscopy (SEM).
The results highlight the considerable potential of these natural hydrogels for the management of chronic wound treatments and microbial infections and draw attention to the advantageous incorporation of Royal Jelly-derived bioactive compounds, providing multiple benefits such as anti-aging, anti-inflammatory and antibacterial properties, while promoting rapid wound healing.
