TI2BioP (Topological Indices to BioPolymers) is a software to estimate topological indices (TIs) from two-dimensional (2D) graphical approaches for the natural biopolymers DNA, RNA and proteins The methodology mainly turns long biopolymeric sequences into 2D artificial graphs such as Cartesian and four-color maps but also reads other 2D graphs from the thermodynamic folding of DNA/RNA strings inferred from other programs. The topology of such 2D graphs is either encoded by node or adjacency matrixes for the calculation of the spectral moments as TIs. These numerical indices were used to build up alignment-free models to the functional classification of biosequences and to calculate alignment-free distances for phylogenetic purposes. We released the version 2.0 of the software that can be freely downloaded from http://ti2biop.sourceforge.net/.
Previous Article in event
Next Article in event
Conception, synthesis, characterization and antimicrobial evaluation of new ferrocene-based derivatives inspired by the bisacodyl lead structureNext Article in congress
TI2BioP: Topological Indices to BioPolymers
Published: 04 December 2015 by MDPI in MOL2NET'15, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 1st ed. congress CHEMBIO.INFO-01: Cheminfo., Chemom., Comput. Quantum Chem. & Bioinfo. Congress, Cambridge, UK-Chapel Hill and Richmond, USA, 2015
Keywords: 2D graphs, Topological indices, Alignment-free models, Phylogenetics