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Graphene-based polymer nanocomposite catalyzed one pot multi-component synthesis of chromene derivatives
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1  Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, P.O. Box 16846-13114 Tehran, I. R. Iran.


Benzochromenes are one of the most important heterocycle compounds which were used as agrochemicals, biological and anticancer agents [1]. Among the various heterogeneous catalysts, graphene-based polymer nanocomposites due to their unique features were used for the synthesis of these kind of compounds. It is a novel and efficient catalyst for the synthesis of chromene derivatives from aldehydes, malononitrile and barbitoric acid [2]. In this research, a simple method including easy work up and high yields with elimination of organic solvents was reported.


 [1] Seyyedi, N., Shirini, F., Langarudi, N., Safarpoor, M., RSC Advances, 6, 44630 – 44640, (2016).

 [2] Wang, L., Lu, X., Lei, S., Song, Y., Journal of Materials Chemistry A, 2, 4491-4509, (2014).

Keywords: HeterocycleS, Benzochromenes, graphene-based polymer nanocomposites