Please login first
A more efficient catalyst for the cycloisomerization of alkynoic acids

A number of terminal and internal alkynoic acids with different substitution patterns have been efficiently cycloisomerized to the corresponding exocyclic enol lactones in the presence of low amounts of a non-symmetric NNC palladium complex and a catalytic amount of triethylamine.

Keywords: alkynoic acid, cycloisomerization, palladium, pincer