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Prediction of RIFIN proteins with gene orientation network indices
* 1, 2 , 2 , 2 , 1 , 3
1  RNASA-IMEDIR, Computer Science Faculty, University of A Coruña, 15071, A Coruña, Spain
2  Universidad Estatal Amazónica
3  Dept. of Organic Chemistry II, University of the Basque Country UPV/EHU, 48940, Leioa, Biscay, Spain


Gene orientation may have a direct influence on the expression of genes. In this work, we developed a Linear Discriminant Analysis (LDA) model able to predict RIFIN-like proteins of out of 5365 of Plasmodium falciparum proteins with Sensitivity and Specificity 70-80% in training and external validation series.

Keywords: Malaria; Plasmodium sp. proteome; Chromosome microstructure; Gene orientation; Complex Networks; Machine Learning