The first synthesis of [1,2]oxaphosphinino[6,5-c]pyrazoles by thiophosphorylation of  6-aminopyrano[2,3-c]pyrazole-5-carbonitriles

¹ Kuban State University, 149 Stavropolskaya Str., Krasnodar 350040, Russian Federation
² ChemEx Lab, Vladimir Dal’ Lugansk National University, Lugansk, 91034 Russia.
³ North-Caucasus Federal University, 1 Pushkina St., 355009 Stavropol, Russian Federation
⁴ V.I. Vernadsky Crimean Federal University, Tavrida Academy, 4 Vernadsky avenue, 295007 Simferopol, Russia

Published: 14 November 2018 by MDPI in The 22nd International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-22-05680

Abstract:

The reaction of 6-amino-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles with phosphorus sulfide in boiling pyridine leads to the formation of the unexpected [1,2]oxaphosphinino[6,5-c]pyrazoles. The structure of the products was confirmed by means of 2D NMR spectroscopy and X-ray analysis.

Keywords: thiophosphorylation, phosphorus (V) sulfide, pyrano[2,3-c]pyrazoles, 1,2-oxaphosphinine, X-ray structural analysis.

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