Nature is an abundant source of drugs, however, it is estimated that only 5 to 15% of the approximately 250,000 species have been studied worldwide. Of the medicinal plants active ingredients of marked importance in the current investigation are obtained. This century has been characterized by the discovery and development of drugs based on an extensive exploration of natural products. There are several factors that enhance these studies: the increase in the withdrawal of drugs due to serious side effects, the increase in bacterial resistance, the resistance of tumor cells to current anticancer treatments, among others. That is why the pharmaceutical industry and researchers of any area are interested in finding new medicines from natural sources. Our objective is the study of Cissus incisa as a potential source of therapeutic agents. As result of the HPLC analysis of the hexane extract, it is obtained that it contains interesting phytocompounds. These compounds are: phytol, β-Sitosterol, α-Amyrin, β-Amyrin and β-Amyrone. Which have previously been repotted biological properties as antimicrobial and anticancer.