Abstract: The development of new antimicrobial and anti cancer therapeutic agents is one of the fundamental goals in medicinal chemistry. Chiral thioureas and their derivatives display a wide range of biological activities such as antibacterial, antiviral and antifungal (1). In addition, some of these compounds could be used as catalysts in the asymmetric reactions such as the Michael addition to nitroalkenes and the Biginelli reaction. Therefore, recent efforts have been devoted to the synthesis of these compounds (2). In the light of this information, novel chiral thioureas bearing amino acids and 2-aminophenol moieties were synthesized in good yields and the structures of the compounds were characterized by elemental analysis, IR, ¹H NMR and ¹³C NMR. References (1) Saeed, S., Rashid, N., Jones, P., Ali, M., Hussain, R., Eur. J. Med. Chem. 45, 2010, 1323-1331 (2) Sheng-Li, Z., Chang-Wu, Z., Gang, Z., Tetrahedron: Asymmetry, 20, 2009, 1046-1051