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[] The role of excipients in neglected tropical diseases

1 Departamento de Farmacia y Tecnología Farmacéutica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramon yCajal s/n, Madrid, 28040, Spain.
2 3Departamento de Farmacia, Facultad de Ciencias de la Salud, Universidad Cardenal Herrera-CEU, Moncada, Valencia, 46113, Spain.
3 School of Pharmacy and Biomedical Sciences, University of Portsmouth, St. Michael’s Building, White Swan Road, Portsmouth PO12DT, U.K.
* Author to whom correspondence should be addressed.
13 October 2017
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Abstract

Leishmaniasis is a neglected tropical disease responsible for the ninth largest disease burden in the world. Excipients are necessary for ensuring the stability and bioavailability of currently available antileishmaniasis drugs. In a recent work, we have evaluated the in vitro activity of 30 commercially available excipients against different Leishmania spp., their cytotoxicity and potential use for inclusion in novel formulations. Ref: Curr Top Med Chem. 2017 Jul 19. https://www.ncbi.nlm.nih.gov/pubmed/28730958

Keywords

Excipients, leishmaniasis, amphiphile, surfactant, lipids, Eudragit, Labrasol, medium chain fatty acids, lauric acid, sodium deoxycholate

Cite this article as

Serrano, D.; Dea-Ayuela, M.; Aikaterini, L. The role of excipients in neglected tropical diseases. In Proceedings of the MOL2NET 2017, International Conference on Multidisciplinary Sciences, 3rd edition, 15 February–20 December 2017; Sciforum Electronic Conference Series, Vol. 3, 2017 ; doi:10.3390/mol2net-03-04621

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