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  • 72 Reads
Greenhouse Gases

Infrared (IR) dynamic gasses, basically water vapor (H2O), carbon dioxide (CO2), and ozone (O3), normally exhibit in the Earth's climate, assimilate warm IR radiation produced by the Earth's surface and environment. The air is warmed by this instrument and, thus, transmits IR radiation, with a noteworthy part of this vitality acting to warm the surface and the lower climate. As an outcome the normal surface air temperature of the Earth is around 30° C higher than it would be without air ingestion and reradiating of IR vitality. This wonder is prominently known as the "nursery impact," and the IR dynamic gasses in charge of the impact are moreover alluded to as "nursery gasses." The fast increment in groupings of nursery gasses since the mechanical period started has offered ascend to worry over potential resultant atmosphere changes.

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  • 141 Reads
Mercury in the Everglades
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Water quality conditions in the Everglades are affected by mercury , the accumulation of mercury in aquatic ecosystems is of global concern due to health effects associated with eating fish with elevated Hg levels. Mercury contamination has been recognized as a critical health issue for humans and wildlife that consume fish from the Everglades. The state of Florida has advisories that restrict consumption of some species of fish

Methylmercury is also produced naturally from inorganic mercury in the aquatic environment by bacteria in sediments under conditions devoid of dissolved oxygen. Once produced, is readily taken up but eliminated by fish . This results in a phenomenon referred to as bioaccumulation. The ratio of the methylmercury concentration in a fish to the concentration in the surrounding water is its bioaccumulation factor (BAF). Fish will bioaccumulate higher concentrations of methylmercury, this results in a phenomenon referred to as biomagnification

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  • 151 Reads
Pollution in Everglades

The Everglade is common called “The river of grass” is most important river for Florida, The Everglades cover about 1,500,000 acres where habit wonderful species of animals and plants, the Everglades also supply fresh water for almost all Florida and it’s a land suitable for farming, the benefits that we receives of this area are a lot, but unfortunately the humans has contaminated this sources of water for many years. The pollution consequences affect all type of being livening in Florida, animals, plants include population Floridian. The Everglades is not only a principal source of water but also is a perfect land for agriculture, since the war world end the farmers began growing vegetable and sugar cane. The Everglades is a home for many species of animals animal and plants that make a wonderful place, but the pollution other factor produced by man to cause problem in this beautiful place.

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  • 178 Reads
Comparative Study of Invasive Candidiasis in Mexico and Spain
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Candida genus includes more than 150 species, including some human pathogens such as Candida albicans, Candida guilliermondii, Candida krusei, Candida parapsilosis, Candida tropicalis, Candida lusitaniae, Candida dubliniensis and Candida glabrata. These fungi are found in non-living objects, food, animals and some of them are part of the human microbiota (mycobiota) without causing disease. Gastrointestinal tract (including oral cavity and pharynx), female genitals and skin are common environments for Candida. Since the introduction of antifungal drugs, the aetiology of invasive candidiasis is a changing from a complete predominance of C. albicans to a more diverse participation from other species, such as C. glabrata or C. parapsilosis (Longo, Fauci, Kasper & Hauser, 2012).

Invasive candidiasis is the most common fungal disease in hospitalized patients. This disease comprises different clinical presentation such as candidemia or different organ or deep tissue infections. Candidemia is the most common presentation. Deep candidiasis is caused by bloodstream dissemination or direct inoculation of the fungus in organs and tissues. Mortality among patients with invasive candidiasis is high (15-40%) (del Palacio, Villar & Alhambra, 2009) even when the patients have been treated with antifungal therapy. This growing incidence from the non-albicans species is worrying because many species are resistant to current antifungal drugs (Kullberg & Arendrup, 2015).

Methods: A systematic bibliographical review was realized, so we could identify and resume all publications related to invasive candidiasis, its clinical characteristics and epidemiology. A relevant article selection was performed, we were guided by title, abstract and the ones that were what we expected were meticulously read and reviewed. National Library of Medicine, Pub-Med search engine was used and papers from 2009 to 2017 were selected. The keywords used are as follows: “Candida”, “Candida and Mexico”, “Candida and Spain”, “Invasive candidiasis”, “Candidemia”, “Candida and Epidemiology” and “Candida and Children”. Finally, a report was made with the most prominent findings.

Conclusion: In Mexico, candidemia in paediatric patients is caused by C. albicans (64%), followed by C. tropicalis (26%), C. glabrata (6%) and C. parapsilosis (2%) (Martínez Garnica, Jiménez Jiménez, Ramírez Guerrero & López Martínez, 2015). In adult patients, C. albicans (62%), followed by C. glabrata (12%), C. tropicalis (7.5%), C. parapsilosis (7.3%), and C. krusei (2.7%) are the most frequently isolated (del Palacio, Villar & Alhambra, 2009).

Spanish paediatric candidiasis are mostly caused by C. parapsilosis (43%), followed by C. albicans (36%). The rest of infections are mainly caused by C. glabrata, C. tropicalis and C. krusei (García-Rodríguez et al., 2013). C. albicans is the fungus most isolated in Spanish adult patients (40-75%), followed by C. glabrata or C. parapsilosis (25%) according to differences in geographical areas, C. tropicalis (10%) and less frequently C. krusei, C. lusitaniae and C. guilliermondii (Gómez, García Vázquez, Hernández, Espinoza & Ruiz, 2010).

Besides the bibliographical review and the writing of an extended written essay, I have been working at the Microbiology laboratory, helping to the realization of several laboratory activities that would help to accomplish the Master Thesis named “Capacidad de desinfección de un aparato de luz ultravioleta y comparación con otros desinfectantes y antisépticos”.

References:

del Palacio, A., Alhambra, A., & Cuetara, M. (2010). Factores de riesgo de la candidiasis invasora: estratificación. Revista Iberoamericana De Micología23(1), 29-31. http://dx.doi.org/10.1016/s1130-1406(06)70009-2

del Palacio, A., Villar, J., & Alhambra, A. (2009). Epidemiología de las candidiasis invasoras en población pediátrica y adulta. Revista Iberoamericana De Micología26(1), 2-7. http://dx.doi.org/10.1016/s1130-1406(09)70002-6

García-Rodríguez, J., Cantón, E., Pemán, J., Alvarez, M., Ezpeleta, G., & Gómez-Nieto, A. et al. (2013). Incidencia etaria y geográfica y patrón de sensibilidad a los antifúngicos de las especies de Candida causantes de candidemia en la población pediátrica española. Enfermedades Infecciosas Y Microbiología Clínica31(6), 363-368. http://dx.doi.org/10.1016/j.eimc.2012.09.018

Gómez, J., García Vázquez, E., Hernández, A., Espinoza, C., & Ruiz, J. (2010). Candidemias nosocomiales: nuevos retos de un problema emergente. Revista Española De Quimioterapia23(4), 158-169.

Kullberg, B., & Arendrup, M. (2015). Invasive Candidiasis. New England Journal Of Medicine373(15), 1445-1456. http://dx.doi.org/10.1056/nejmra1315399

Longo, D., Fauci, A., Kasper, D., & Hauser, S. (2012). Harrison. Principios de Medicina Interna (12th ed.). México: McGraw-Hill Interamericana.

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  • 87 Reads
Overview of PT-QSRR models for predicting yield of reaction

In organic chemistry the prediction of yield of reaction Yld(%) is very important. In almost all cases, organic chemists infer qualitatively the yield of a query reaction Yld(%)new taking into consideration the experimental results for a previous reaction of reference Yld(%)ref.  The PT-QSRR models are a quantitative expression of this idea because they applied Perturbation Theory (PT) to seek Quantitative Structure-Reactivity Relationship models. PT-QSRR predict the yield of some reactions comparing quantitatively the molecular properties of components such as catalyst, substrate, product, and nucleophile as well as controlled variables such as time, temperature and catalyst loading of both the new reaction and the reaction of reference. Other authors have previously developed a PT-QSPR approach, which combines perturbation theory (PT) and QSRR ideas, to correlate and predict different outputs (properties) in complex molecular systems (metabolic reactions) nanoparticles, and so forth (1). The method has also been extended to predict the enantioselectivity and/or yield of intramolecular carbolithiation and Heck–Heck cascade reactions (2). In some cases, the developed PT-QSRR models use trace operators, like spectral moments, or eigenvalues of chemical structure matrices, like bond adjacency matrix, as the inputs.

 Methods

The molecular descriptors of type k, structural variables, Vk(Mi) are calculated for each molecule Mi in both reactions. Next, the deviations ΔVk(Mi) = Vk(Mi)new - Vk(Mi)ref, can be used to quantify the structural perturbations or structural changes in the new molecules with respect to the query ones. In the same form deviation operators canc be used to measure perturbations on variables Vk(cj) depending on  the experimental conditions cj, ΔVk(cj) = Vk(cj)new - Vk(cj)ref.

References

  1. H. Gonzalez-Diaz, S.  Arrasate,  A.  Gmez-SanJuan,  N.  Sotomayor, E.  Lete, L. Besada-Porto, J. M. Ruso, Curr. Top. Med. Chem. 2013, 13, 1713 –1741.
  2. H. Gonzalez-Diaz, S. Arrasate, A. Gjmez-SanJuan, N. Sotomayor, E. Lete, A.  Speck-Planche,  J. M.  Ruso,  F.  Luan,  M. N.  Cordeiro,  Curr.  Drug Metab. 2014, 15, 470 –488.
  3. C. R. Munteanu, J. Dorado, A. Pazos Sierra, F. Prado-Prado, L. G. P8rez- Montoto, S. Vilar, F. M. Ubeira, A. S#nchez-Gonz#lez, M. Cruz Monteagu- do,  S.   Arrasate,  N.   Sotomayor,  E.   Lete,   A.  Duardo-S#nchez,   A.  D&az- Ljpez,  G.  Patlewicz,  H.  Gonz#lez-D&az  in  Towards  an  Information  Theory of Complex  Networks.  Statistical  Methods  and  Applications  (Eds.:  M.  Dehmer, F. Emmert-Streib, A. Mehler), Springer, Basel,  2011,  pp. 199 – 258
  4. H. Gonzalez-Diaz, S. Arrasate, A. Gjmez-SanJuan, N. Sotomayor, E. Lete, A.  Speck-Planche,  J. M.  Ruso,  F.  Luan,  M. N.  Cordeiro,  Curr.  Drug Metab. 2014, 15, 470 –488.
  • Open access
  • 159 Reads
Editorial: EHUDW01, First EHU-DELFIN Program Workshop, Bilbao, Jul, 201
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The UPVEHUDW01: First UPV-EHU DELFIN Program Workshop, Bilbao, Jul, 2017 is a scientific and educational workshop organized by professors of the University of the Basque Country (UPV/EHU) and IKERBASQUE, Basque Foundation for Sciences.  The workshops is associated to the MOL2NET International Conference Series on Multidisciplinary Sciences, MDPI Sciforum, Basel, Switzerland. The workshop aim is to promote the scientific, educational, and cultural interchange of professors and students of UPV/EHU with students of the international education network DELFIN, Mexico. The DELFIN program was created in 1995 with the aim of strengthening the collaborative culture between the Higher Education Institutions and Research Centers that are members of the Program, through the mobility of professors-researchers, students and the dissemination of scientific and technological products. In particular, the workshop aims to strengthen the development of research and national graduate. Specifically, student mobility is promoted through academic research stays, within the framework of the Summer of Scientific and Technological Research of the Pacific. This mobility program strengthens the vocation of young people for science and technology and influences their decision to join postgraduate programs at home and abroad.

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Worldwide cyber-attacks: their impact on the international health services and their answer in the Spanish criminal code

On 12th May 2017, many health services around the world suffered the attack of the “WannaCry” ransomware. This paper exposes the main consequences faced by them in the United States, Great Britain, Germany, Australia, New Zealand and Spain, and the possibilities according to the Spanish Criminal Code of prosecuting this kind of crimes, demonstrating that we must secure the internal excellence of each individual health service, promote the development of new, more technical articles in the mentioned legal text and, above all, strengthen the international cooperation in order to effectively prosecute these attacks.

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  • 158 Reads
Biotechnology in plants genomics: a legal and bioethics overview.

Concepts like bio-security and bioethics have been put into the test whit the rapid advance of the Biotechnology. Specifically the plant’s genome manipulation is worthy to be reconsidered by the ethical and juridical point of views. Plants varieties and products obtained by these new biotechnological methods are important achievements but also can be a risk for the human health and the environment. On the other hand, a monopoly of commercial exploitation for the holder of the patent and other exclusives titles like Certificates of Vegetable Obtaining can leave out the fair access to the technological progresses. In this work we make a valuation about those aspects of Biotechnology related with the genome of the plants and their juridical protection.

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Challenges in Law, Technology, Life, and Social Sciences

The interaction between bio-science and ICTs has forged great developments in many fields. However, the appreciation of these discoveries is sadly, all too often, accompanied by a lack of understanding of the legal implications. This conference series aims to provide a reference to the various legal avenues that are available for the protection of scientific advances, but also the legal instruments to protect society from unwanted effects.

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Climate Change and the National Park Everglades

The National Park Everglades is already damaged by the warming climate. The sea level is rising and has already brought several changes to the landscape. In the future these changes will be worse.The Everglades as we call them, find their origins 3200 years ago, when the rhythm of rising seas dropped significantly from 9 inches to 1.5 inches per century. This dropped of the tide rise in the sea level allowed an urbanization of mud, shells and sand at the Florida’s Southern Coast. This kind of ridge acted as a low dam and stopped ocean water from crossing over it. This natural dam hinder rainfall and overflow from Lake Okeechobee forming a freshwater environment, the Everglades.  A large portion of this exceptional landscape is now protected as Everglades National Park.

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