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Synthesis of novel benzoannelated eight-membered heterocycles: easy access to benzo[f][1,4]oxazocin-1-ones
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1  Laboratoire d’Ingénierie Moléculaire et Biochimie Pharmacologique, Université Paul Verlaine - Metz, 1 Boulevard Arago, 57070 METZ, France

Abstract: Medium-sized N-heterocycles, in particular eight-membered azocines, are key structures occurring in many natural products and in some compounds having biological activities. We described here an easy access to benzo[f][1,4]oxazocin-1-ones starting from 2-acetylbenzoic acid.
Keywords: eight-membered N, O heterocycles, ethanolamines, ZnCl<sub>2</sub>

 
 
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