A synthesis of 4-methylumbelliferyl-ß-D-glucopyranosiduronic acid

M. A. López-López; A. Balbuzano-Deus; J. C. Rodríguez-Domínguez; M. Hernández; A. Villalobo; Y. Reyes; G. Kirsch

doi:10.3390/ecsoc-10-01396

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A synthesis of 4-methylumbelliferyl-ß-D-glucopyranosiduronic acid

M. A. López-López

¹,

A. Balbuzano-Deus

¹,

J. C. Rodríguez-Domínguez

^{*

1, 2},

M. Mesa Hernández

¹,

A. Fernández Villalobo

¹,

Y. Ibarra Reyes

¹,

G. Kirsch

^{*

2}

¹ Departamento de Química, Centro de Química Farmacéutica, Calle 200 y 21, Atabey, Playa, CP: 11600, Ciudad de la Habana, Cuba
² Laboratoire d´Ingénierie Moléculaire et Biochimie Pharmacologique, 1, Boulevard Arago, 57070, Metz, France

Published: 30 November 2006 by MDPI in The 10th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-10-01396

Abstract: A synthetic route to prepare 4-methylumbelliferyl-ß-D-glucopyranosiduronic acid (MUG) from 4-methylumbelliferyl-ß-D-glucopyranoside (MUGluc) was developed affording the MUG with an overall yield of 37 % from the MUGluc.

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M. A. López-López

A. Balbuzano-Deus

J. C. Rodríguez-Domínguez

M. Hernández

A. Villalobo

Y. Reyes

G. Kirsch