New Synthesis of 4,4'-Diethylaminoethoxyhexestrol dihydrochloride (Coralgil) and scaling up to multi-grams scale

Behrooz Yousef; Ulrich Jordis Jordis

doi:10.3390/ecsoc-10-01415

x Selected file doesn't exist!

Previous Article in event

Synthesis and characterization of new Mannich base ligand. Structure of N, N-bis-(4,5-dimethyl-2-hydroxybenzyl)-N(2-pyridylmethyl)amine

Next Article in event

Probing The Resolution of 2-Alkoxy and 2-Aryloxy Carboxylic Acids

New Synthesis of 4,4'-Diethylaminoethoxyhexestrol dihydrochloride (Coralgil) and scaling up to multi-grams scale

Behrooz H. Yousef

Ulrich Jordis Jordis

¹ Institute of Applied Synthetic Chemistry, Vienna University of Technology, Austria

Published: 30 November 2006 by MDPI in The 10th International Electronic Conference on Synthetic Organic Chemistry session Bioorganic Chemistry and Natural Products

https://doi.org/10.3390/ecsoc-10-01415

Abstract: We report here new preparation with significant yield improvement of title compound. For this purpose the preparation of 4,4'-diethylaminoethoxyhexestrol dihydrochloride under different reported and analogue conditions have been tried. The optimized synthesis of Coralgil is reported. The synthesis was also scaled up to multi-grams for chemo-genomics study.

Keywords: n/a

View paper

32 Reads
0 Recommendations

Behrooz Yousef

Ulrich Jordis Jordis