Substituted Quinolinones. Part 14. Synthesis of Novel Dispiro(heterocycle-n,2'-[1,3]dithietane-4',3"-quinolinedione) Derivatives Under PTC-conditions

Ahmed Khodairy; Mohamed Abass

doi:10.3390/ecsoc-14-00464

x Selected file doesn't exist!

Previous Article in event

Microwave synthesis of [6-Diethylamino-9-(2-octylcarbamoyl-phenyl)-xanthen-3-ylidene]-diethyl-amine and its isomer

Previous Article in session

Synthesis and Characterization of Manganese (III) tetra (4- methoxyphenyl) porphyrin encapsulated in zeolite –X: as efficient catalyst for the hydroxylation of Thymol

Next Article in event

A QSAR analysis of some amino substituted Pyrido[3,2-b]pyrazinones as potent and selective PDE-5 inhibitors

Next Article in session

Synthesis of Conformationally Restricted Glycoamino Acids using Fluorinating Agents

Substituted Quinolinones. Part 14. Synthesis of Novel Dispiro(heterocycle-n,2'-[1,3]dithietane-4',3"-quinolinedione) Derivatives Under PTC-conditions

Ahmed Khodairy

¹,

Mohamed Abass

¹ Chemistry Department, Faculty of Science, Sohag University, Postal Code 82524, Sohag, Egypt
² Chemistry Department, Faculty of Education, Ain Shams University, Postal Code 11757, Cairo, Egypt

Published: 30 October 2010 by MDPI in The 14th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-14-00464

Abstract: The four-membered spiro-heterocycles; ethyl cyano(1-methyl-2,4-dioxospiro{1,3-quinoline-3,4'-[1,3]dithietane}-4'-ylidene)- acetate 2a, -malononitrile 2b, -acetylacetone 2c and thiazetidine isomer 3 were prepared under phase transfer catalysis conditions (PTC). The thermal treatment of dithietanes 2a–c led to the bis-quinolinyl sulfide 4. Some interesting nucleophilic addition followed by cyclization reactions were carried out with the dithietane 2a to give the corresponding novel dispiro derivatives 5–8, 10–13, and 15.

View paper

59 Reads
0 Recommendations

Ahmed Khodairy

Mohamed Abass