Previous Article in event
Next Article in event Next Article in session
Facile Synthesis of Bis(azolyl) Derivatives in a Superbasic Medium
Published: 30 October 2012 by MDPI in The 16th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis
Abstract: Reaction of azoles (1,2,4-triazole, benzimidazole, bezotriazole) and dihalogenoderivatives of alkanes and oligoethyleneglykols in a superbasic KOH-dimethylsulfoxide medium was used for the synthesis of bis(azolyl)alkanes and related compounds. The new method does not involve the use of toxic solvents and catalysts, does not require column chromatography for product separation and gives the target compounds in high yields.
Keywords: 1,2,4-triazole, benzimidazole, bezotriazole, alkylation, superbacis medium