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Ethyl 2-(Diisopropoxyphosphoryl)-2H-Azirine-3-Carboxylate: Reactions with Activated 1,3-Butadienes
* 1 , 2 , 3 , 4
1  Departamento de Química, Universidade do Minho, Campus de Gualtar, 4710-057 Braga, Portugal
2  Departamento de Química, Bioquímica e Farmácia, Universidade do Algarve, Campus de Gambelas, 8005-137 Faro, Portugal
3  CIQ, Departamento de Química, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre, 687, 4169-007 Porto, Portugal
4  Departamento de Química Orgánica, Facultade de Farmacia, Universidade de Santiago de Compostela, E-15782 Santiago de Compostela, Spain

Abstract: Ethyl 2-(diisopropoxyphosphoryl)-2H-azirine-3-carboxylate was generated “in situ” and reacted with a number of 1,3-butadienes. Cycloadducts, or in one case an ensuing rearranged product, were isolated with moderate to good yields.
Keywords: 2H-Azirines, aza-Diels-Alder cycloaddition, dienophiles, phosphonate derivative compounds