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Phytochemical, antioxidant and antimicrobial characterization of lavandula angustifolia extract
* 1 , 1 , 2 , 1 , 1, 3 , 1 , 1 , 1
3  Faculty of Pharmacy, University Titu Maiorescu of Bucharest, Bucharest, 040441, Romania
Academic Editor: Humbert G. Díaz


The present research describes the components of the lavender (Lavandula angustifolia) plant extract. Lavender is a shrub native from Mediterranean region and belongs to the family Lamiaceae1. The scientifical literature2,3 detailed the fact that lavender flowers content anthocyanins, polyphenols, flavonoids, sugars, minerals, and tannins and essential oil (approx. 3%), which have a lot of health benefits (antioxidant, antibacterial, antimicrobial properties)4,5, due to their components. Also, lavender oil is one of the most valuable aromatherapy oils, its anti-bacterial and anti-fungal activities due to his main components (linalool, geraniol, eucalyptol, etc)6,7. The aim of our study was to characterize qualitative (tannins, saponins, alkaloids) and quantitative (polyphenols, flavonoids, anthocyanins) screening for phytochemical compounds and antioxidant activity of the ethanolic and hydroalcoholic extracts obtained from lavender flowers at 2 different temperatures (20°C and 45°C) using ultrasound bath. The samples were analyzed by FTIR and UV-VIS techniques. The antioxidant activity was evaluated using DPPH method. The antioxidant activity of hydroalcoholic extracts shows higher results than ethanolic extracts, regardless of the extraction temperature used. The antimicrobial activity of lavender extract was demonstrated on Candida albicans, Escherichia coli and Staphylococcus aureus. The results indicated the fact that for E. coli and C. albicans extracts 1 and 3 proven similar efficiency, but higher by spot application than disc.


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  2. Aroma Characteristics of Lavender Extract and Essential Oil from Lavandula angustifolia Mill. Guo, P. Wang, Molecules, vol. 25, no. 5541, 14 pp, 2020.
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  4. Anti-infammatory efect of lavender (Lavandula angustifolia Mill.) essential oil prepared during diferent plant phenophases on THP-1 macrophages E. Pandur, A. Balatinácz, G. Micalizzi, L. Mondello, A. Horváth, K. Sipos, G. Horváth, BMC Complementary Medicine and Therapies, vol. 21, no. 287, 17 pp, 2021.
  5. Toxicity assessment of Lavandula officinalis extracts in Brine Shrimp (Artemia salina), W.L. Braguini, B.B. Alves, N.V. Pires, TOXICOLOGY MECHANISMS AND METHODS, 4 pp, 2019.
  6. Phytochemical Screening and Antidermatophytic Activity of Lavender Essential Oil from Saudi Arabia, S. Khayyat, M. Al-Kattan, N. Basudan, International Journal of Pharmacology, vol. 14, no. 6, pag. 802-810, 2018.
  7. Chemical Composition of Two Different Lavender Essential Oils and Their Effect on Facial Skin Microbiota, Białoń, T. Krzyśko-Łupicka, E. Nowakowska-Bogdan, P.P. Wieczorek, Molecules, vol. 24, no. 18: 3270, 17 pp, 2019.

Keywords: flavonoids, polyphenols, antioxidant and antimicrobial activity, UV-VIS determinations
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Maider Baltasar Marchueta
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Hello, can please explain why you have chosen two temperatures 20° and 45 °C ?

can climate change affect the quality and quantity of the different components of the lavender flower?